Peer Reviewed Publications:
Leishman DJ, Holdsworth DL, Lauver DA, Bailie MB, Roche BM. The “One-Step” approach for QT analysis increases the sensitivity of nonclinical QTc analysis. Clin Transl Sci. 2023 Sep 19. doi: 10.1111/cts.13625. PMID: 37726963.
Kuszynski DS, Christian BD, Bernard MP, Lauver DA. Evaluation of the Efficacy and Safety of Antiplatelet Therapeutics in Rabbits. Curr Protoc. 2023 Mar;3(3):e711. doi: 10.1002/cpz1.711. PMID: 36921209.
Ether ND, Leishman DJ, Bailie MB, Lauver DA. QT Ratio: A simple solution to individual QT correction. J Pharmacol Toxicol Methods. 2022 Sep-Oct;117:107211. doi: 10.1016/j.vascn.2022.107211. Epub 2022 Aug 22. PMID: 36007862.
Kuszynski DS, Lauver DA. Pleiotropic effects of clopidogrel. Purinergic Signal. 2022 Sep;18(3):253-265. doi: 10.1007/s11302-022-09876-0. Epub 2022 Jun 9. PMID: 35678974; PMCID: PMC9391547.
Ether ND, Jantre SR, Sharma DB, Leishman DJ, Bailie MB, Lauver DA. Improving corrected QT; Why individual correction is not enough. J Pharmacol Toxicol Methods. 2022 Jan-Feb;113:107126. doi: 10.1016/j.vascn.2021.107126. Epub 2021 Oct 13. PMID: 34655760.
Kuszynski DS, Christian BD, Dorrance AM, Lauver DA. Clopidogrel treatment inhibits P2Y2-Mediated constriction in the rabbit middle cerebral artery. Eur J Pharmacol. 2021 Nov 15;911:174545. doi: 10.1016/j.ejphar.2021.174545. Epub 2021 Oct 2. PMID: 34606835; PMCID: PMC8577565.
Ether N, Leishman D, Bailie M, Lauver A. Relationship of clinical adverse event reports to models of arrhythmia risk. Journal of Pharmacological and Toxicological Methods. 2019 Aug 6;100:106622. PMID: 31398384
Lauver DA*, Kuszynski DS, Christian BD, Bernard MP, Teuber JP, Markham BE, Chen YE, Zhang H. DT-678 Inhibits Platelet Activation with Lower Tendency for Bleeding Compared to Existing P2Y12 Antagonists. Pharmacology Research and Perspectives. 2019 Jul 25;7(4):e00509. PMCID: PMC6658415 *Corresponding author
Gurm HS, Seth M, Dixon SR, Grossman PM, Sukul D, Lalonde T, Cannon L, West D, Madder RD, Lauver DA. Contemporary use of and outcomes associated with ultra-low contrast volume in patients undergoing percutaneous coronary interventions. Catheter Cardiovasc Interv. 2019 Feb 1;93(2):222-230. doi: 10.1002/ccd.27819. Epub 2018 Aug 25. PMID: 30144337.
Zhang H, Lauver DA, Wang H, Sun D, Hollenberg PF, Chen YE, Osawa Y, Eitzman DT. Significant Improvement of Antithrombotic Responses to Clopidogrel by Use of a Novel Conjugate as Revealed in an Arterial Model of Thrombosis. The Journal of Pharmacology and Experimental Therapeutics. 2016 Oct;359(1):11-7.
Lauver DA*, Carey EG, Bergin IL, Lucchesi BR, Gurm HS. Sildenafil citrate for prophylaxis of nephropathy in an animal model of contrast-induced acute kidney injury. PLoS One. 2014 Nov 26;9(11):e113598. *Corresponding author
Zhang H, Lauver DA, Hollenberg PF. CYP-independent inhibition of platelet aggregation in rabbits by a mixed disulfide conjugate of clopidogrel. Thrombosis and Haemostasis. 2014 Dec 1;112(6):1304-11.
Zhang H, Lauver DA, Lucchesi BR, Hollenberg PF. Formation, reactivity, and antiplatelet activity of mixed disulfide conjugates of clopidogrel. Molecular Pharmacology. April 2013; 83(4):848-856.
Lauver DA, Kaissarian NM, Lucchesi BR. Oral pretreatment with liposomal glutathione attenuates reperfusion injury in rabbit isolated hearts. Journal of Cardiovascular Pharmacology. Mar 2013; 61(3):233-239.
Lauver DA*, Rimon G*, Sidhu RS*, Lee JY, Sharma NP, Yuan C, Frieler RA, Trievel RC, Lucchesi BR, Smith WL. Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1. Proceedings of the National Academy of Science. Jan 5 2010;107(1):28-33. * D.A.L., G.R., and R.S.S., contributed equally to this work.
Lauver DA, Driscoll EM, Lucchesi BR. Disodium Disuccinate Astaxanthin Prevents Carotid Artery Rethrombosis and ex vivo Platelet Activation. Pharmacology. May 14 2008;82(1):67-73.
Lauver DA, Lucchesi BR. Sulodexide: a renewed interest in this glycosaminoglycan. Cardiovascular Drug Reviews. Fall-Winter 2006;24(3-4):214-226.
Lauver DA, Lockwood SF, Lucchesi BR. Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. The Journal of Pharmacology and Experimental Therapeutics. Aug 2005;314(2):686-692.
Lauver DA, Booth EA, White AJ, Poradosu E, Lucchesi BR. Sulodexide attenuates myocardial ischemia/reperfusion injury and the deposition of C-reactive protein in areas of infarction without affecting hemostasis. The Journal of Pharmacology and Experimental Therapeutics. Feb 2005;312(2):794-800.
Wang X, Dorsam RT, Lauver DA, Wang H, Barbera FA, Gibbs S, Varon D, Savion N, Friedman SM, Feuerstein GZ. Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion. The Journal of Pharmacology and Experimental Therapeutics. Dec 2002;303(3):1114-1120.
Non-Peer Reviewed Publications
Lauver DA. Remembering Dr. Benedict Robert Lucchesi (1933-2020). The Pharmacologist. Sept 2020;62(3):164-166.